Eirik Bratland Selected Research

Steroid 21-Hydroxylase (21 Hydroxylase)

4/2021	The natural history of 21-hydroxylase autoantibodies in autoimmune Addison's disease.
1/2021	21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison's Disease Are Restricted by HLA-A2 and HLA-C7 Molecules.
3/2015	Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression analysis.
12/2014	CYP21A2 polymorphisms in patients with autoimmune Addison's disease, and linkage disequilibrium to HLA risk alleles.
1/2014	Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia.
12/2009	T cell responses to steroid cytochrome P450 21-hydroxylase in patients with autoimmune primary adrenal insufficiency.
8/2009	The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: the major autoantigen in autoimmune Addison's disease.
5/2006	The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope.

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Eirik Bratland Research Topics

Disease

13	Addison Disease (Addison's Disease) 04/2021 - 05/2006
3	type 1 Autoimmune polyendocrinopathy syndrome 01/2017 - 06/2013
2	Autoimmune Diseases (Autoimmune Disease) 11/2021 - 01/2021
2	Infections 08/2018 - 03/2016
2	Dental Enamel Hypoplasia 01/2016 - 06/2013
1	Hypopituitarism (Sheehan's Syndrome) 01/2022
1	Holoprosencephaly (Arhinencephaly) 01/2022
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Neoplasms (Cancer) 01/2020
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2019
1	Hyperandrogenism 01/2019
1	Persistent Infection 08/2018
1	Giardiasis 08/2018
1	Mycoses (Diseases, Fungus) 01/2017
1	Chronic Mucocutaneous Candidiasis 01/2017
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016
1	Hypoparathyroidism 01/2016
1	Seizures (Absence Seizure) 12/2015
1	Hypocalcemia 12/2015
1	Intestinal Hypomagnesemia 1 12/2015
1	Immune System Diseases (Immune Disorders) 06/2014
1	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/2014
1	Virus Diseases (Viral Diseases) 01/2013
1	Adrenocortical Carcinoma 01/2013

Drug/Important Bio-Agent (IBA)

8	Steroid 21-Hydroxylase (21 Hydroxylase)IBA 04/2021 - 05/2006
7	AutoantibodiesIBA 04/2021 - 08/2009
4	InterferonsIBA 03/2016 - 01/2013
3	EnzymesIBA 04/2021 - 05/2006
3	EpitopesIBA 01/2021 - 12/2009
3	SteroidsIBA 01/2019 - 08/2009
3	AntibodiesIBA 08/2018 - 06/2013
3	AutoantigensIBA 12/2014 - 05/2006
2	CytokinesIBA 01/2017 - 01/2013
2	AntigensIBA 01/2016 - 04/2011
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 12/2009 - 08/2009
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 11/2021
1	Biomarkers (Surrogate Marker)IBA 03/2021
1	GlucocorticoidsIBA 03/2021
1	HLA-A2 Antigen (HLA A2 Antigen)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Temozolomide (Temodar)FDA LinkGeneric 01/2020
1	MethyltransferasesIBA 01/2020
1	Bortezomib (Velcade)FDA Link 01/2020
1	Toll-Like Receptor 3IBA 04/2019
1	Dehydroepiandrosterone SulfateIBA 01/2019
1	Dehydroepiandrosterone (DHEA)IBA 01/2019
1	SaltsIBA 01/2019
1	PregnenoloneIBA 01/2019
1	Immunoglobulin G (IgG)IBA 08/2018
1	Membrane Proteins (Integral Membrane Proteins)IBA 08/2018
1	Immunoglobulin A (IgA)IBA 08/2018
1	Interleukin-17 (Interleukin 17)IBA 01/2017
1	InterleukinsIBA 01/2017
1	Interleukin-23 (Interleukin 23)IBA 01/2017
1	MagnesiumIBA 12/2015
1	ChemokinesIBA 10/2015
1	Interleukin-2 (IL2)IBA 03/2015
1	Interferon Type IIBA 07/2014
1	Hormones (Hormone)IBA 06/2014
1	Tryptophan HydroxylaseIBA 06/2013
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 06/2013
1	Mixed Function Oxygenases (Monooxygenases)IBA 06/2013
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 06/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013
1	Poly I-CIBA 01/2013
1	LigandsIBA 01/2013
1	CXC ChemokinesIBA 01/2013
1	HLA Antigens (Human Leukocyte Antigens)IBA 12/2009
1	Amino Acids FDA Link 12/2009
1	HLA-DRB1 Chains (HLA DRB1)IBA 12/2009
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 05/2006

Therapy/Procedure

1	Combined Modality Therapy 01/2020
1	Therapeutics 04/2011